Open AccessModafinil Use in Psychiatric Disorders
Author(s) -
Mehmet Hanifi Kokaçya,
Mit Copoglu,
Musa Şahpolat,
Mustafa Arı
Publication year - 2015
Publication title -
psikiyatride güncel yaklaşımlar/psikiyatride güncel yaklaşımlar
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.108
H-Index - 1
eISSN - 1309-0674
pISSN - 1309-0658
DOI - 10.5455/cap.20150525104841
Subject(s) - modafinil , psychiatry , medicine , psychology
Modafinil, is a psychostimulant drug with neurochemical and behavourial effects, distinct from those of amphetamine. It is used to treat patients with narcolepsy and other excessive sleepiness. Modafinil has dopaminergic, noradrenergic, histaminergic, glutamergic, serotonergic and GABAergic interactions. It is also shown that modafinil has neuroprotective effects via antioxidative mechanisms. Besides modafinil shows initial promise for a variety of off-label indications in psychiatry, including bipolar disorder, attention-deficit/hyperactivity disorder, and schizophrenia . The aim of this article is to review the literature on clinical use of modafinil in psychiatric disorders. [Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 2016; 8(1): 42-51