Higher fibroblast growth factor-23 concentrations associate with left ventricular systolic dysfunction in dialysis patients | Zendy

Shailendra Sharma | Zendy; Jacob Joseph | Zendy; Michel Chonchol | Zendy; James S. Kaufman | Zendy; Alfred K. Cheung | Zendy; Zahi Rafeq | Zendy; Gerard Smits | Zendy; Jessica Kendrick | Zendy; the HOST Investigators | Zendy

Open Access

Higher fibroblast growth factor-23 concentrations associate with left ventricular systolic dysfunction in dialysis patients

Author(s) -

Shailendra Sharma,

Jacob Joseph,

Michel Chonchol,

James S. Kaufman,

Alfred K. Cheung,

Zahi Rafeq,

Gerard Smits,

Jessica Kendrick,

the HOST Investigators

Publication year - 2013

Publication title -

clinical nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.314

H-Index - 75

ISSN - 0301-0430

DOI - 10.5414/cn107991

Subject(s) - medicine , fibroblast growth factor 23 , ejection fraction , left ventricular hypertrophy , cardiology , dialysis , diabetes mellitus , hemodialysis , blood pressure , pathogenesis , endocrinology , fgf21 , fibroblast growth factor , heart failure , receptor , parathyroid hormone , calcium

The concentration of fibroblast growth factor 23 (FGF-23) is elevated in patients on dialysis. FGF receptors have been implicated in the pathogenesis of left ventricular (LV) hypertrophy. The objective of this study was to examine the associations between high plasma FGF-23 concentration and LV systolic dysfunction.

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