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Radiographic Contrast-Media-Induced Acute Kidney Injury: Pathophysiology and Prophylactic Strategies
Author(s) -
Umar Sadat
Publication year - 2013
Publication title -
isrn radiology
Language(s) - English
Resource type - Journals
ISSN - 2314-4084
DOI - 10.5402/2013/496438
Subject(s) - medicine , acute kidney injury , pathophysiology , incidence (geometry) , contrast (vision) , intensive care medicine , physics , artificial intelligence , computer science , optics
Contrast-induced acute kidney injury (CI-AKI) is one of the most widely discussed and debated topics in cardiovascular medicine. With increasing number of contrast-media- (CM-) enhanced imaging studies being performed and growing octogenarian population with significant comorbidities, incidence of CI-AKI remains high. In this review, pathophysiology of CI-AKI, its relationship with different types of CM, role of serum and urinary biomarkers for diagnosing CI-AKI, and various prophylactic strategies used for nephroprotection against CI-AKI are discussed in detail.

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