Hypertension: The Neglected Complication of Transplantation | Zendy

Lucas S. Aparicio | Zendy; José Alfie | Zendy; Jessica Barochiner | Zendy; Paula E. Cuffaro | Zendy; Marcelo A. Rada | Zendy; Margarita S. Morales | Zendy; Carlos Galarza | Zendy; Gabriel Waisman | Zendy

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Hypertension: The Neglected Complication of Transplantation

Author(s) -

Lucas S. Aparicio,

José Alfie,

Jessica Barochiner,

Paula E. Cuffaro,

Marcelo A. Rada,

Margarita S. Morales,

Carlos Galarza,

Gabriel Waisman

Publication year - 2013

Publication title -

isrn hypertension

Language(s) - English

Resource type - Journals

ISSN - 2090-8709

DOI - 10.5402/2013/165937

Subject(s) - calcineurin , complication , transplantation , medicine , intensive care medicine , perspective (graphical) , pathophysiology , surgery , computer science , artificial intelligence

Arterial hypertension and transplantation are closely linked, and its association may promote impaired graft and overall survival. Since the introduction of calcineurin inhibitors, it is observed in 50–80% of transplanted patients. However, many pathophysiological mechanisms are involved in its genesis. In this review, we intend to provide an updated overview of these mechanisms, dealing with the causes common to all kinds of transplantation and emphasizing special cases with distinct features, and to give a perspective on the pharmacological approach, in order to help clinicians in the management of this frequent complication.

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