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Mass Spectrometry for Diabetic Nephropathy Monitoring: New Effective Tools for Physicians
Author(s) -
Annunziata Lapolla,
Susanna Porcu,
Pietro Traldi
Publication year - 2012
Publication title -
isrn endocrinology
Language(s) - English
Resource type - Journals
eISSN - 2090-4649
pISSN - 2090-4630
DOI - 10.5402/2012/768159
Subject(s) - metabolome , diabetic nephropathy , mass spectrometry , proteome , nephropathy , medicine , metabolomics , computational biology , computer science , chromatography , diabetes mellitus , bioinformatics , chemistry , endocrinology , biology
The main aim of diabetic nephropathy monitoring is to identify molecular markers, that is, to find changes occurring at metabolome and proteome levels indicative of the disease's development. The mass spectrometry methods available today have been successfully applied to this field. This paper provides a short description of the basic aspects of the mass spectrometric methods used for diabetic nephropathy monitoring, reporting and discussing the results obtained using different approaches.

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