Intracoronary Imaging and Histopathology of Late Phase In-Stent Restenosis after Coronary Stent Implantation | Zendy

Shigenori Ito | Zendy; Kosuke Nakasuka | Zendy; Satoru Sekimoto | Zendy; Kazuyuki Miyata | Zendy; Masahiko Inomata | Zendy; Takayuki Yoshida | Zendy; Nozomu Tamai | Zendy; Tomoaki Saeki | Zendy; Shin Suzuki | Zendy; Yoshimasa Murakami | Zendy; Kōichi Sato | Zendy

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Intracoronary Imaging and Histopathology of Late Phase In-Stent Restenosis after Coronary Stent Implantation

Author(s) -

Shigenori Ito,

Kosuke Nakasuka,

Satoru Sekimoto,

Kazuyuki Miyata,

Masahiko Inomata,

Takayuki Yoshida,

Nozomu Tamai,

Tomoaki Saeki,

Shin Suzuki,

Yoshimasa Murakami,

Kōichi Sato

Publication year - 2012

Publication title -

isrn vascular medicine

Language(s) - English

Resource type - Journals

eISSN - 2090-5831

pISSN - 2090-5823

DOI - 10.5402/2012/678137

Subject(s) - restenosis , stent , histopathology , medicine , bare metal stent , angioplasty , intimal hyperplasia , cardiology , coronary restenosis , radiology , drug eluting stent , pathology , smooth muscle

In the field of coronary artery stenting, restenosis issue has been almost resolved after development of drug-eluting stents (DESs). In-stent restenosis (ISR) is generally considered to be a stable process, with an early peak in intimal hyperplasia followed by a quiescent period beginning 1 year after stent implantation. However, recently, extended-term problem (over 1 year) in both bare-metal stents (BMSs) and DES has been reported. This phenomenon seems to be different from early ISR within one year in terms of its mechanism, prevention, and treatment. In this paper, we discuss this topic from the standpoint of intracoronary imagings and histopathology, referencing several interesting cases we experienced.

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