Anti-Inflammatory, Analgesic, and Antipyretic Activities of the Ethanol Extract of Piper interruptum Opiz. and Piper chaba Linn. | Zendy

Seewaboon Sireeratawong | Zendy; Arunporn Itharat | Zendy; Nusiri Lerdvuthisopon | Zendy; Pritsana Piyabhan | Zendy; Parirat Khonsung | Zendy; S. Boonraeng | Zendy; Kanjana Jaijoy | Zendy

Open Access

Anti-Inflammatory, Analgesic, and Antipyretic Activities of the Ethanol Extract of Piper interruptum Opiz. and Piper chaba Linn.

Author(s) -

Seewaboon Sireeratawong,

Arunporn Itharat,

Nusiri Lerdvuthisopon,

Pritsana Piyabhan,

Parirat Khonsung,

S. Boonraeng,

Kanjana Jaijoy

Publication year - 2012

Publication title -

isrn pharmacology

Language(s) - English

Resource type - Journals

eISSN - 2090-5173

pISSN - 2090-5165

DOI - 10.5402/2012/480265

Subject(s) - piperaceae , carrageenan , antipyretic , piper , analgesic , traditional medicine , granuloma , edema , body weight , medicine , pharmacology , surgery , immunology

Piper interruptum Opiz. and Piper chaba Linn. are herbaceous plants in the Piperaceae family. The ethanol extract of P. interruptum and P. chaba inhibited ethyl phenylpropiolate-induced ear edema and carrageenan-induced hind paw edema in rats. Both extracts reduced transudative and granuloma weights as well as body weight gain and thymus weight of the chronic inflammatory model using cotton pellet-induced granuloma formation in rats. Moreover, both extracts exhibited analgesic activity on both early phase and late phase of formalin test in mice and also showed antipyretic activity on yeast-induced hyperthermia in rats.

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