18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Management of Aggressive Non-Hodgkin's B-Cell Lymphoma
Author(s) -
Martin J. Shelly,
Shaunagh McDermott,
Owen J. O’Connor,
Michael A. Blake
Publication year - 2012
Publication title -
isrn hematology
Language(s) - English
Resource type - Journals
eISSN - 2090-4428
pISSN - 2090-441X
DOI - 10.5402/2012/456706
Subject(s) - medicine , lymphoma , positron emission tomography , radiology , fluorodeoxyglucose , nuclear medicine , follicular lymphoma , positron emission tomography computed tomography , stage (stratigraphy) , radiation therapy , computed tomography , pathology , paleontology , biology
18-Fluorodeoxyglucose (FDG-PET/CT) is an established imaging modality that has been proven to be of benefit in the management of aggressive B-cell non-Hodgkin's lymphoma, such as diffuse large B-cell lymphoma and advanced stage follicular lymphoma. The combination of anatomic and functional imaging afforded by FDG-PET/CT has led to superior sensitivity and specificity in the primary staging, restaging, and assessment of response to treatment of hematological malignancies when compared to FDG-PET and CT alone. The use of FDG-PET/CT for posttreatment surveillance imaging remains controversial, and further study is needed to ascertain whether this modality is cost effective and appropriate for use in this setting.
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