Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention) | Zendy

Akke Vellinga | Zendy; Agnieszka Zawiejska | Zendy; Jürgen Harreiter | Zendy; Brian S Buckley | Zendy; Graziano Di Cianni | Zendy; Annunziata Lapolla | Zendy; Rosa Corcoy | Zendy; David Simmons | Zendy; Juan M. Adelantado | Zendy; Peter Damm | Zendy; Gernot Desoyé | Zendy; Roland Devlieger | Zendy; David J. Hill | Zendy; Alexandra KautzkyWiller | Zendy; Miira M. Klemetti | Zendy; Elisabeth R. Mathiesen | Zendy; Pablo Rebollo | Zendy; Frank J. Snoek | Zendy; Minna Tikkanen | Zendy; D. Timmerman | Zendy; Ado Van Assche | Zendy; Mireille N. M. van Poppel | Zendy; Ewa Wender-Oėgowska | Zendy; Fidelma Dunne | Zendy

Open Access

Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention)

Author(s) -

Akke Vellinga,

Agnieszka Zawiejska,

Jürgen Harreiter,

Brian S Buckley,

Graziano Di Cianni,

Annunziata Lapolla,

Rosa Corcoy,

David Simmons,

Juan M. Adelantado,

Peter Damm,

Gernot Desoyé,

Roland Devlieger,

David J. Hill,

Alexandra KautzkyWiller,

Miira M. Klemetti,

Elisabeth R. Mathiesen,

Pablo Rebollo,

Frank J. Snoek,

Minna Tikkanen,

D. Timmerman,

Ado Van Assche,

Mireille N. M. van Poppel,

Ewa Wender-Oėgowska,

Fidelma Dunne

Publication year - 2012

Publication title -

isrn obesity

Language(s) - English

Resource type - Journals

ISSN - 2090-9446

DOI - 10.5402/2012/424010

Subject(s) - gestational diabetes , medicine , obstetrics , body mass index , pregnancy , obesity , caesarean section , population , diabetes mellitus , gynecology , gestation , endocrinology , environmental health , genetics , biology

Objective . Assess the impact of Gestational Diabetes Mellitus (GDM) and obesity on neonatal and maternal pregnancy outcomes. Methods . Cross-sectional data (3343 pregnancies) from seven European centres were included in a multilevel analysis of the association between GDM/obesity and caesarean section, macrosomia and neonatal morbidities. Results . Comparison of databases identified reporting differences between countries due to the inclusion of true population based samples or pregnancies from specialised tertiary centres, resulting in higher prevalences of GDM for some countries. The analysis showed that obesity and GDM were independent risk factors of perinatal complications. Only BMI had a dose-dependent effect on the risk of macrosomia and caesarean section. Both obesity (BMI > 30 kg/m 2 ) and GDM were independent risk factors of neonatal morbidities. Conclusions . Obesity and GDM were independent risk factors of perinatal complications. The effect of the worldwide obesity and diabetes epidemic is extending to the next generation.

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