Open AccessA Green, Expeditious, One-Pot Synthesis of 3, 4-Dihydropyrimidin-2(1H)-ones Using a Mixture of Phosphorus Pentoxide-Methanesulfonic Acid at Ambient Temperature
Author(s) -
Amulrao U. Borse,
Mahesh N. Patil,
Nilesh B. Patil,
Rohan Shinde
Publication year - 2012
Publication title -
isrn organic chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-5157
pISSN - 2090-5149
DOI - 10.5402/2012/415645
Subject(s) - methanesulfonic acid , phosphorus pentoxide , phosphorus , chemistry , pentoxide , organic chemistry , vanadium
An expeditious, one-pot method for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones using a mixture of phosphorus pentoxide-methanesulfonic acid (Eaton's reagent) at room temperature under solvent-free conditions is described. The salient features of this method include short reaction time, green aspects, high yields, and simple procedure.
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