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High-Resolution Optical Imaging of Benign and Malignant Mucosa in the Upper Aerodigestive Tract: An Atlas for Image-Guided Surgery
Author(s) -
Lauren Levy,
Peter M. Vila,
Richard W. Park,
Richard A. Schwarz,
Alexandros D. Polydorides,
Marita S. Teng,
Vivek V. Gurudutt,
Eric M. Genden,
Brett A. Miles,
Sharmila Anandasabapathy,
Ann M. Gillenwater,
Rebecca Richards–Kortum,
Andrew G. Sikora
Publication year - 2012
Publication title -
isrn minimally invasive surgery
Language(s) - English
Resource type - Journals
ISSN - 2090-9438
DOI - 10.5402/2012/364285
Subject(s) - medicine , pathology , esophagus , larynx , oral mucosa , epithelium , radiology , anatomy
High-resolution optical imaging provides real-time visualization of mucosa in the upper aerodigestive tract (UADT) which allows non-invasive discrimination of benign and neoplastic epithelium. The high-resolution microendoscope (HRME) utilizes a fiberoptic probe in conjunction with a tissue contrast agent to display nuclei and cellular architecture. This technology has broad potential applications to intraoperative margin detection and early cancer detection.

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