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Assessing the Impact of Increasing Antimicrobial Resistance of Vibrio cholerae on the Future Trends of Cholera Epidemic
Author(s) -
Steady Mushayabasa,
C. P. Bhunu
Publication year - 2012
Publication title -
isrn biomathematics
Language(s) - English
Resource type - Journals
ISSN - 2090-7702
DOI - 10.5402/2012/127492
Subject(s) - vibrio cholerae , cholera , antimicrobial , antibiotic resistance , microbiology and biotechnology , vibrionaceae , biology , virology , geography , bacteria , antibiotics , genetics
Cholera, an acute intestinal infection caused by the bacterium Vibrio cholerae , remains a major public health problem in many parts of Africa, Asia, and Latin America. A mathematical model is developed, to assess the impact of increasing antimicrobial resistance of Vibrio cholerae on the future trends of the cholera epidemic. Equilibrium states of the model are determined and their stabilities have been examined. The impacts of increasing antimicrobial resistance of Vibrio cholerae on the future trends of cholera epidemic have been investigated through the reproductive number. Numerical results are provided to support analytical findings.

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