Antioxidant Activity of β-Glucan
Author(s) -
Kyoko Kofuji,
Ayumi Aoki,
Kazufumi Tsubaki,
Masanori Konishi,
Takashi Isobe,
Yoshifumi Murata
Publication year - 2012
Publication title -
isrn pharmaceutics
Language(s) - English
Resource type - Journals
eISSN - 2090-6153
pISSN - 2090-6145
DOI - 10.5402/2012/125864
Subject(s) - antioxidant , glucan , beta glucan , food science , chemistry , oxidative stress , antioxidant capacity , biochemistry , excipient , chromatography
β -Glucans extracted from barley, which mainly contains β -(1,3-1,4)- D -glucan, are used extensively as supplements and food additives due to their wide biologic activities, including a reduction in blood lipid level. In this study, the antioxidant activity of β -glucan was examined to assess potential new benefits associated with β -glucan, because oxidative stress is considered one of the primary causal factors for various diseases and aging. β -Glucan extracted from barley was found to possess significant antioxidant activity. The amount of antioxidant activity was influenced by different physiologic properties (e.g., structure and molecular size) of β -glucan, which varied depending on the source and extraction method used. The antioxidant activity of β -glucan was significantly higher than that of various polymers that are used as food additives. These results indicate that β -glucan has promise as a polymeric excipient for supplement and food additive with antioxidant and other benefits, which may contribute to enhancing health and beauty.
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