Cancers of the Appendix: Review of the Literatures
Author(s) -
Carl Alex Ruoff,
Louay Hanna,
Wanqing Iris Zhi,
Ghulamullah Shahzad,
Vladimir Gotlieb,
Muhammad Wasif Saif
Publication year - 2011
Publication title -
isrn oncology
Language(s) - English
Resource type - Journals
eISSN - 2090-567X
pISSN - 2090-5661
DOI - 10.5402/2011/728579
Subject(s) - appendix , medicine , asymptomatic , right hemicolectomy , adenocarcinoma , general surgery , chemotherapy , lymph node , appendicitis , randomized controlled trial , surgery , cancer , colorectal cancer , paleontology , biology
Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of appendix are only 0.08% of all cancers and the treatment remains controversial. Here we are reporting a 46-year-old male presented with symptoms of appendicitis, diagnosed with adenocarcinoma of the appendix. The patient was treated with appendectomy and refused further surgical intervention to complete hemicolectomy. Up to date, he remains asymptomatic. We performed literature review of the tumors of the appendix. Most of the benign conditions are treated with surgery alone. Lymphomas require CHOP-like chemotherapy and carcinoid syndrome treatment with somatostatin analogues. It is generally recommended that right hemicolectomy is the preferred treatment for adenocarcinoma of appendix. The role of chemotherapy is unclear due to lacking randomized trials but seems to be accepted if there is lymph node involvement or peritoneal seeding.
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