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Hexane, ethyl acetate, ethanol and methanol extracts of  Psidium guajava, Terminalia chebula, Mimusops elengi and Achyranthes aspera  were tested against the dental caries causing bacteria  Streptococcus mutans  and fungus  Candida albicans  isolated from caries infected patients. All the four extracts of  P. guajava  showed activity against both  S. mutans  and  C. albicans . Maximum zone of inhibition was observed in ethyl acetate of  P. guajava . The four extracts of  T. chebula  and  M.  elengi  showed antibacterial activity against  S.  mutans .  M. elengi  extracts and ethanol extract of  T. chebula  did not show any antifungal activity against  C. albicans . Except for the hexane extract of  A. aspera , the other three extracts showed activity against the tested microbes. The ethyl acetate  P. guajava  leaf extract showed the minimum inhibitory concentration (MIC) against  S.  mutans  to be <0.076 mg/mL in both MHB and BHI. The  P. guajava  ethyl acetate extract was subjected to GC-MS.

Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study