Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study | Zendy

H. Shyla Jebashree | Zendy; S. Kingsley | Zendy; Emmanuel Solomon Sathish | Zendy; D. Devapriya | Zendy

Open Access

Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study

Author(s) -

H. Shyla Jebashree,

S. Kingsley,

Emmanuel Solomon Sathish,

D. Devapriya

Publication year - 2011

Publication title -

isrn dentistry

Language(s) - English

Resource type - Journals

eISSN - 2090-438X

pISSN - 2090-4371

DOI - 10.5402/2011/541421

Subject(s) - streptococcus mutans , ethyl acetate , candida albicans , terminalia chebula , psidium , antimicrobial , traditional medicine , chemistry , antibacterial activity , ethanol , microbiology and biotechnology , minimum inhibitory concentration , corpus albicans , bacteria , biology , biochemistry , botany , medicine , organic chemistry , genetics

Hexane, ethyl acetate, ethanol and methanol extracts of Psidium guajava, Terminalia chebula, Mimusops elengi and Achyranthes aspera were tested against the dental caries causing bacteria Streptococcus mutans and fungus Candida albicans isolated from caries infected patients. All the four extracts of P. guajava showed activity against both S. mutans and C. albicans . Maximum zone of inhibition was observed in ethyl acetate of P. guajava . The four extracts of T. chebula and M. elengi showed antibacterial activity against S. mutans . M. elengi extracts and ethanol extract of T. chebula did not show any antifungal activity against C. albicans . Except for the hexane extract of A. aspera , the other three extracts showed activity against the tested microbes. The ethyl acetate P. guajava leaf extract showed the minimum inhibitory concentration (MIC) against S. mutans to be <0.076 mg/mL in both MHB and BHI. The P. guajava ethyl acetate extract was subjected to GC-MS.

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