Age at Menarche, Menstrual Characteristics, and Risk of Preeclampsia | Zendy

Dejene Abetew | Zendy; Daniel A. Enquobahrie | Zendy; Michal Dishi | Zendy; Carole B. Rudra | Zendy; Raymond Miller | Zendy; Michelle A. Williams | Zendy

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Age at Menarche, Menstrual Characteristics, and Risk of Preeclampsia

Author(s) -

Dejene Abetew,

Daniel A. Enquobahrie,

Michal Dishi,

Carole B. Rudra,

Raymond Miller,

Michelle A. Williams

Publication year - 2011

Publication title -

isrn obstetrics and gynecology

Language(s) - English

Resource type - Journals

eISSN - 2090-4444

pISSN - 2090-4436

DOI - 10.5402/2011/472083

Subject(s) - menarche , odds ratio , preeclampsia , medicine , confidence interval , logistic regression , body mass index , obstetrics , pregnancy , algorithm , gynecology , mathematics , demography , biology , genetics , sociology

We examined associations of age at menarche and menstrual characteristics with the risk of preeclampsia among participants ( n = 3,365) of a pregnancy cohort study. Data were collected using in-person interviews and medical record abstraction. Logistic regression was used to estimate adjusted odds ratio (OR) and 95% confidence interval (95% CI). There was a significant inverse association between age at menarche and risk of preeclampsia ( P value for trend < 0.05). Association of long cycle length (>36 days) with higher risk of preeclampsia was present only among women who had prepregnancy body mass index <25 kg/m 2 (interaction P value = 0.04). Early menarche is associated with higher risk of preeclampsia. Prepregnancy weight may modify associations of long menstrual cycles with risk of preeclampsia.

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