Bupropion extended-release induced spontaneous orgasms | Zendy

Mehmet Hamdi Örüm | Zendy; Oğuzhan Bekir Eğilmez | Zendy; Aysun Kalenderoǧlu | Zendy

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Bupropion extended-release induced spontaneous orgasms

Author(s) -

Mehmet Hamdi Örüm,

Oğuzhan Bekir Eğilmez,

Aysun Kalenderoǧlu

Publication year - 2018

Publication title -

dusunen adam the journal of psychiatry and neurological sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.205

H-Index - 12

ISSN - 1018-8681

DOI - 10.5350/dajpn2018310112

Subject(s) - bupropion , dopamine , antidepressant , anesthesia , medicine , norepinephrine , pharmacology , psychology , smoking cessation , hippocampus , pathology

Bupropion extended-release induced spontaneous orgasms Sexual side effects are common with antidepressant use. Spontaneous orgasms have been previously described with several antidepressants. We report the case of a woman who had spontaneous orgasms after starting 300mg/day bupropion extended-release. Spontaneous orgasms ceased 4 days after stopping the bupropion extended-release. Bupropion extended-release is a norepinephrine-dopamine reuptake inhibitor. Norepinephrineand dopamine-related mechanisms may induce spontaneous orgasms. This unusual side effect should be questioned in patients who receive bupropion, as it may cause embarrassment and noncompliance.

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