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CTS Trials Network: A paradigm shift in the surgical treatment of moderate ischemic mitral regurgitation?
Author(s) -
Ahmed Afifi
Publication year - 2015
Publication title -
global cardiology science and practice
Language(s) - English
Resource type - Journals
ISSN - 2305-7823
DOI - 10.5339/gcsp.2015.30
Subject(s) - medicine , cardiology , mitral regurgitation , clinical endpoint , bypass grafting , randomized controlled trial , clinical trial , mitral valve repair , artery , mitral valve , surgery
The Cardiothoracic Surgery Trials Network has reported results of the one-year follow up of their randomized trial "Surgical Treatment of Moderate Ischemic Mitral Regurgitation". They studied 301 patients with moderate ischemic mitral regurgitation (IMR) undergoing coronary artery bypass grafting (CABG) with or without mitral repair with the primary end-point of change in left ventricular end-diastolic volume index (LVEDVI) at one year and multiple clinical and echocardiographic secondary endpoints. Although their results were against repairing the mitral valve, the debate on surgical management of moderate IMR remains unsettled.

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