Computational fluid dynamics applied to virtually deployed drug-eluting coronary bioresorbable scaffolds: Clinical translations derived from a proof-of-concept
Author(s) -
Bill D. Gogas,
Boyi Yang,
Tiziano Passerini,
Alessandro Veneziani,
Marina Piccinelli,
Gaetano Esposito,
Emad Rasoul–Arzrumly,
Mosaab Awad,
Girum Mekonnen,
Olivia Y. Hung,
Beth Holloway,
Michael McDaniel,
Don P. Giddens,
Spencer B. King,
Habib Samady
Publication year - 2014
Publication title -
global cardiology science and practice
Language(s) - English
Resource type - Journals
ISSN - 2305-7823
DOI - 10.5339/gcsp.2014.56
Subject(s) - proof of concept , bioresorbable scaffold , drug , computer science , biomedical engineering , cardiology , medicine , percutaneous coronary intervention , myocardial infarction , pharmacology , operating system
Three-dimensional design simulations of coronary metallic stents utilizing mathematical and computational algorithms have emerged as important tools for understanding biomechanical stent properties, predicting the interaction of the implanted platform with the adjacent tissue, and informing stent design enhancements. Herein, we demonstrate the hemodynamic implications following virtual implantation of bioresorbable scaffolds using finite element methods and advanced computational fluid dynamics (CFD) simulations to visualize the device-flow interaction immediately after implantation and following scaffold resorption over time.
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