Reprogramming for cardiac regeneration | Zendy

Christophe M. Raynaud | Zendy; Faizzan S. Ahmad | Zendy; Mona Allouba | Zendy; Haissam Abou-Saleh | Zendy; Kathy O. Lui | Zendy; Magdi H. Yacoub | Zendy

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Reprogramming for cardiac regeneration

Author(s) -

Christophe M. Raynaud,

Faizzan S. Ahmad,

Mona Allouba,

Haissam Abou-Saleh,

Kathy O. Lui,

Magdi H. Yacoub

Publication year - 2014

Publication title -

global cardiology science and practice

Language(s) - English

Resource type - Journals

ISSN - 2305-7823

DOI - 10.5339/gcsp.2014.44

Subject(s) - reprogramming , regeneration (biology) , medicine , focus (optics) , bioinformatics , microbiology and biotechnology , biology , cell , genetics , physics , optics

Treatment of cardiovascular diseases remains challenging considering the limited regeneration capacity of the heart muscle. Developments of reprogramming strategies to create in vitro and in vivo cardiomyocytes have been the focus point of a considerable amount of research in the past decades. The choice of cells to employ, the state-of-the-art methods for different reprogramming strategies, and their promises and future challenges before clinical entry, are all discussed here.

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