High Frequency Deep Brain Stimulation of Superior Cerebellar Peduncles in a Patient with Cerebral Palsy | Zendy

Suzhen Lin | Zendy; Chencheng Zhang | Zendy; Hongxia Li | Zendy; Yuhan Wang | Zendy; Yunhao Wu | Zendy; Tao Wang | Zendy; Yixin Pan | Zendy; Bomin Sun | Zendy; Yiwen Wu | Zendy; Dianyou Li | Zendy

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High Frequency Deep Brain Stimulation of Superior Cerebellar Peduncles in a Patient with Cerebral Palsy

Author(s) -

Suzhen Lin,

Chencheng Zhang,

Hongxia Li,

Yuhan Wang,

Yunhao Wu,

Tao Wang,

Yixin Pan,

Bomin Sun,

Yiwen Wu,

Dianyou Li

Publication year - 2020

Publication title -

tremor and other hyperkinetic movements

Language(s) - English

Resource type - Journals

ISSN - 2160-8288

DOI - 10.5334/tohm.551

Subject(s) - dystonia , deep brain stimulation , cerebral palsy , spasticity , medicine , physical medicine and rehabilitation , movement disorders , stimulation , neuroscience , psychology , parkinson's disease , disease

Background: Globus pallidus internus (GPi) deep brain stimulation (DBS) is widely used in patients with isolated dystonia; however, its use remains controversial in patients with acquired dystonia and cerebral palsy. Case presentation: We report the first case of a cerebral palsy patient, who failed to recover 2 years after GPi DBS; DBS was administered on both superior cerebellar peduncles (SCPs) and dentate nuclei (DNs). The monopolar stimulation results suggested that DBS was better administered via the SCPs than via the DNs. At six months follow-up, the patient exhibited a significant improvement of dystonia and spasticity, as well as in her quality of life. Discussion: SCP DBS may be a potential treatment for cerebral palsy patients with dystonia and spasticity who do not respond well to GPi DBS.

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