Breast Lymphoma

An 80-year-old man was referred to the radiology department because of a persisting palpable mass in the left breast. Family history of breast cancer was negative. The mammography revealed a retro-areolar mass in the left breast (Figure 1). There were no microcalcifications. Ultrasound of the left breast showed predominantly enlarged mammary ducts, apparently caused by an ill-defined hypo-echogenic retro-areolar mass of 2.8 cm in diameter (Figure 2). An ultrasound-guided needle core biopsy of the retro-areolar mass was performed. Histology revealed a primary diffuse large B-cell type lymphoma of the breast. The patient had no prior history of lymphoma. Additional PET–CT showed a metabolic active lesion in the left breast (Figure 3). Widespread disease was not present.