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Case 1. A 16-year-old female patient with a history of Diamond-Blackfan Anemia (DBA) treated with repeated transfusions every 3-4 weeks and chelation therapy since infancy presents with transient syncope. Her symptoms progress to include headache, dizziness, and numbness of her right arm, right side of her face, lips, and tongue. MRI of the brain was performed, demonstrating a small frontal subarachnoid hemorrhage (not shown) and dark signal intensity throughout the choroid plexus (Fig. A, B) on susceptibility-weighted imaging (SWI).

Transfusional iron overload presenting as choroid plexus hemosiderosis