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The Impact of Cardiac-induced Post-traumatic Stress Disorder Symptoms on Cardiovascular Outcomes: Design and Rationale of the Prospective Observational Reactions to Acute Care and Hospitalizations (ReACH) Study
Author(s) -
Jeffrey L. Birk,
Ian M. Kronish,
Bernard Chang,
Talea Cornelius,
Marwah Abdalla,
Joseph E. Schwartz,
Joan Duer-Hefele,
Alexandra Sullivan,
Donald Edmondson
Publication year - 2019
Publication title -
health psychology bulletin
Language(s) - English
Resource type - Journals
ISSN - 2398-5941
DOI - 10.5334/hpb.16
Subject(s) - medicine , acute coronary syndrome , emergency department , observational study , prospective cohort study , cohort study , psychosocial , disease , emergency medicine , psychiatry , myocardial infarction
As many as 1 in 8 acute coronary syndrome (ACS) patients develop posttraumatic stress disorder (PTSD) due to the ACS, and ACS-induced PTSD may increase secondary cardiovascular disease (CVD) risk. However, prior studies have been small and underpowered to test plausible behavioral or biological mechanisms of the hypothesized PTSD-secondary CVD risk association. In this paper, we describe the design and methods of a large prospective observational cohort study to estimate the prognostic significance of ACS-induced PTSD, mechanisms for its association with CVD risk, and emergency department (ED) factors that may increase PTSD risk, in a cohort of patients evaluated for acute coronary syndrome (ACS) in the ED of a large, urban academic medical center.

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