The Inhibitory Effects of Polysaccharide Peptides (PsP) ofGanoderma lucidumagainst Atherosclerosis in Rats with Dyslipidemia | Zendy

Titin Andri Wihastuti | Zendy; Teuku Heriansyah | Zendy

Open Access

The Inhibitory Effects of Polysaccharide Peptides (PsP) ofGanoderma lucidumagainst Atherosclerosis in Rats with Dyslipidemia

Author(s) -

Titin Andri Wihastuti,

Teuku Heriansyah

Publication year - 2017

Publication title -

heart international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.183

H-Index - 12

eISSN - 2036-2579

pISSN - 1826-1868

DOI - 10.5301/heartint.5000234

Subject(s) - dyslipidemia , medicine , oxidative stress , antioxidant , endocrinology , endothelial dysfunction , blood lipids , diabetes mellitus , cholesterol , biochemistry , chemistry

Atherosclerosis occurs as a result of low-density lipoprotein (LDL) deposits oxidation. Endothelial dysfunction is an early process of atherosclerosis. Restoring endothelial lining back to normal by endothelial progenitor cells (EPCs) is critical for slowing or reversing vascular disease progression. Oxidative stress from hydrogen peroxide (H 2 O 2 ) is increased in dyslipidemia so that antioxidant agent is required to prevent destruction of blood vessels.

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