RNA Sequencing of Early-Stage Gastric Adenocarcinoma Reveals Multiple Activated Pathways and Novel Long Non-Coding RNAs in Patient Tissue Samples | Zendy

Sadegh Fattahi | Zendy; Novin Nikbakhsh | Zendy; Hassan Taheri | Zendy; Mohammad Ranaee | Zendy; Haleh AkhavanNiaki | Zendy

Open Access

RNA Sequencing of Early-Stage Gastric Adenocarcinoma Reveals Multiple Activated Pathways and Novel Long Non-Coding RNAs in Patient Tissue Samples

Author(s) -

Sadegh Fattahi,

Novin Nikbakhsh,

Hassan Taheri,

Mohammad Ranaee,

Haleh AkhavanNiaki

Publication year - 2021

Publication title -

reports of biochemistry and molecular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.467

H-Index - 8

ISSN - 2322-3480

DOI - 10.52547/rbmb.9.4.478

Subject(s) - biology , transcriptome , gene , rna , carcinogenesis , long non coding rna , antisense rna , computational biology , deep sequencing , cancer , genetics , gene expression , genome

Gastric cancer is among the most common cancers worldwide that currently lacks effective diagnostic biomarkers and therapeutic targets. Next-generation RNA sequencing is a powerful tool that allows rapid and accurate transcriptome-wide profiling to detect differentially expressed transcripts involved in normal biological and pathological processes. Given the function of this technique, it has the potential to identify new molecular targets for the early diagnosis of disease, particularly in gastric adenocarcinoma.

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