Association of vitamin D receptor polymorphisms (Fok1 (rs2228570), ApaI (rs7975232), BsmI (rs1544410), and TaqI (rs731236)) with gastric cancer among Kurdish population from west of Iran | Zendy

Zohreh Hoseinkhani | Zendy; Mohsen RastegariPouyani | Zendy; Farahnaz Tajemiri | Zendy; Kheirollah Yari | Zendy; Kamran Mansouri | Zendy

Open Access

Association of vitamin D receptor polymorphisms (Fok1 (rs2228570), ApaI (rs7975232), BsmI (rs1544410), and TaqI (rs731236)) with gastric cancer among Kurdish population from west of Iran

Author(s) -

Zohreh Hoseinkhani,

Mohsen RastegariPouyani,

Farahnaz Tajemiri,

Kheirollah Yari,

Kamran Mansouri

Publication year - 2021

Publication title -

reports of biochemistry and molecular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.467

H-Index - 8

ISSN - 2322-3480

DOI - 10.52547/rbmb.9.4.435

Subject(s) - foki , taqi , calcitriol receptor , medicine , genotype , restriction fragment length polymorphism , gastroenterology , population , endocrinology , vitamin d and neurology , genetics , polymorphism (computer science) , biology , gene , environmental health

The association of 1,25-dihydroxy vitamin D3 (1,25(OH)2D3) and its receptor, vitamin D receptor (VDR), with cancer types have been studied. However, there are controversial findings regarding the association of specific VDR polymorphisms with different kinds of cancers. In the current study, we investigated the association of VDR polymorphisms (Fok1 (rs2228570), ApaI (rs7975232), BsmI (rs1544410), and TaqI (rs731236)) with the risk of gastric cancer in a Kurdish population of Kermanshah in Iran for the first time.

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