Open AccessConcomitant Up-Regulation of Hsa- Mir-374 and Down-Regulation of Its Targets, GSK-3β and APC, in Tissue Samples of Colorectal Cancer
Author(s) -
Mohammad Reza Bayatiani,
Azam Ahmadi,
Reza Aghabozorgi,
Fatemeh Seif
Publication year - 2021
Publication title -
reports of biochemistry and molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.467
H-Index - 8
ISSN - 2322-3480
DOI - 10.52547/rbmb.9.4.408
Subject(s) - colorectal cancer , concomitant , cancer , oncology , microrna , medicine , cancer research , biology , gene , genetics
The WNT -pathway is involved in several cancers, including colorectal cancer (CRC). Many cell signaling components and pathways are controlled by microRNAs. The main purpose of the present study was to investigate the expression of hsa-miR-374 , and its two target genes of the Wnt -pathway in CRC clinical samples.
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