Open AccessAnti-neuroinflammatory of Chloroform Extract of Panax ginseng Root Culture on Lipopolysaccharide-stimulated BV2 Microglia Cells
Author(s) -
Chee Hoe Cheah,
Anna Pick Kiong Ling,
Ying Pei Wong,
Rhun Yian Koh,
Sobri Hussein,
Agrotechnology and Biosciences Division, Malaysian Nuclear Agency, Bangi, Kajang, Selangor, Malaysia.
Publication year - 2022
Publication title -
reports of biochemistry and molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.467
H-Index - 8
ISSN - 2322-3480
DOI - 10.52547/rbmb.11.1.125
Subject(s) - lipopolysaccharide , ginseng , microglia , chloroform , araliaceae , traditional medicine , chemistry , pharmacology , medicine , immunology , inflammation , chromatography , pathology , alternative medicine
It is believed that activation of microglia in the central nervous system upon detection of stimulus like lipopolysaccharides provokes neuroinflammation via the production of pro-inflammatory mediators and cytokines. The cytoprotective and anti-inflammatory properties of various folk medicine has been gaining attention as a strategy to combat various disease. This study aimed to assess the anti-neuroinflammatory properties of chloroform extract of in vitro Panax ginseng root culture based on nitric oxide and cytokines production.
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