Pre Transplantation Serum Parathyroid Hormone Influences the Number of Mobilized CD34 + Hematopoietic Stem Cells in Autologous Hematopoietic Stem Cell Transplantation | Zendy

Abdolhamed Kian | Zendy; Sayeh Parkhideh | Zendy; Haniyeh GhaffariNazari | Zendy; Maryam Nikoonezhad | Zendy; Arsalan Jalili | Zendy; Shaghayegh Shahsavan | Zendy; Abbas Hajifathali | Zendy

Open Access

Pre Transplantation Serum Parathyroid Hormone Influences the Number of Mobilized CD34 + Hematopoietic Stem Cells in Autologous Hematopoietic Stem Cell Transplantation

Author(s) -

Abdolhamed Kian,

Sayeh Parkhideh,

Haniyeh GhaffariNazari,

Maryam Nikoonezhad,

Arsalan Jalili,

Shaghayegh Shahsavan,

Abbas Hajifathali

Publication year - 2021

Publication title -

reports of biochemistry and molecular biology

Language(s) - English

Resource type - Journals

ISSN - 2322-3480

DOI - 10.52547/rbmb.10.1.76

Subject(s) - transplantation , stem cell , haematopoiesis , cd34 , hematopoietic stem cell transplantation , medicine , parathyroid hormone , cancer research , biology , immunology , microbiology and biotechnology , calcium

Parathyroid hormone (PTH) is a calcium homeostasis regulator and can affect bone marrow niche. PTH leads to the bone marrow stem cell niche expansion as well as the induction of stem cell mobilization from the bone marrow into peripheral blood. In this study, we evaluated the association between pre- transplantation serum PTH levels and the number of circulating CD34+ cells along with the platelets/white blood cells (Plt/WBC) engraftment in patients who underwent autologous Hematopoietic Stem Cell Transplantation.

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