Open AccessDownregulation of Stemness Genes and Induction of Necrosis in Rat LA7 Cancer Stem Cells Induced Tumors Treated with Starved Fibroblasts Culture Supernatant
Author(s) -
Roghayeh Pourbagher,
Hossein Ghorbani,
Haleh AkhavanNiaki,
Seyed Gholam Ali Jorsaraei,
Sadegh Fattahi,
Sahar Ghooran,
Zeinab Abedian,
Masoumeh Ghasemi,
Fatemeh Saeedi,
Negar Jafari,
Behnam Kalali,
Amrollah Mostafazadeh
Publication year - 2021
Publication title -
reports of biochemistry and molecular biology
Language(s) - English
Resource type - Journals
ISSN - 2322-3480
DOI - 10.52547/rbmb.10.1.105
Subject(s) - homeobox protein nanog , stem cell , biology , cancer stem cell , immunohistochemistry , pathology , h&e stain , cytokeratin , stem cell marker , microbiology and biotechnology , cancer cell , cancer research , cancer , induced pluripotent stem cell , medicine , embryonic stem cell , immunology , gene , genetics , biochemistry
Stem cell differentiation therapy is a promising strategy in cancer treatment. we show that protein cocktail prepared from serum starved fibroblasts has therapeutic potential based on this strategy.
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