Antibacterial Activity of Several Indonesian Endemic Plants against Staphylococcus epidermidis, Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus

In this current era, infectious diseases worldwide is increasing and due to misuse of antibiotics for treating infections eventually leads to the emergence of antibiotic resistant microbes. As a country with abundance of natural resources, Indonesia must be the forefront on research in finding new antibacterial candidates resourced from endemic medicinal plants. The objective of this research is to assesed the activities of several Indonesian endemic plants extract to inhibit several bacteria in-vitro by microdilutin method to obtain Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) and agar diffusion method to obtain inhibition zone. In this study, extract of Syzigium aromaticum, Piper betle and Aleurites moluccana were show anti bacterial activity against MRSA (Methicillin-resistant Staphylococcus aureus), Staphylococcus aureus and Staphylococcus epidermidis. On the other hand, extract of Curucuma longa and Samanea saman didnt show any anti bacterial properties. This study show the potency of several endemic plants extract to inhibit Staphylococcal bacteria.