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This presentation outlines the creation of a Provincial Epidemiological and Information Centre (PEIC) in Zambia’s Luapula province. This is only the second epidemiosurveillance centre in the country. Luapula province in the northern part of Zambia being one of only 3 provinces out of a total of 10 provinces that are free of theilleriosis in Zambia has the potential of being Zambia’s largest disease free zone. The challenges as well as lessons learnt from setting up this epidemiosurveillance centre are presented.

Establishing an epidemiosurveillance centre in a resource-constrained setting: A Zambian experience