Magnetic core/gold shell nanoparticle immunoassay for rapid detection of biomolecules using Raman spectroscopy
Author(s) -
Roland Agoston
Publication year - 2016
Language(s) - English
Resource type - Dissertations/theses
DOI - 10.5204/thesis.eprints.97978
Subject(s) - biomolecule , nanotechnology , raman spectroscopy , raman scattering , nanomaterials , nanoparticle , colloidal gold , materials science , surface enhanced raman spectroscopy , molecule , immunoassay , chemistry , physics , optics , organic chemistry , antibody , immunology , biology
Nanomaterials were adorned with recognition molecules and combined with surface-enhanced Raman scattering to selectively separate, identify, and quantify trace amounts of bioactive molecules from within a complex mixture. This work is presented as a rapid, portable, and cost-effective method that complements existing biomolecule analysis techniques, with potential in-field applications in clinical diagnostics, environmental monitoring, and forensic science
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