Anti-Viral Response of Bronchial Epithelial Cells in Adults with Chronic Obstructive Pulmonary Disease (COPD)

This project was an investigation of the antiviral response of lung cells from people with chronic obstructive pulmonary disease (COPD). A novel 3D culture method was used to mimic a real-life airway epithelium. By using this model we found that COPD results in a switch in the type of interferon the cells produce, which has an effect on the antiviral response and will inform the use of interferon as a treatment.