Evaluation of In vitro and In vivo Drug Efficacy Over Leishmania tropica: A Pilot Study
Author(s) -
Ahmet Özbilgin,
İbrahim Çavuş,
Ahmet Yıldırım,
Tuğba Kaya,
Hatice Ertabaklar
Publication year - 2018
Publication title -
turkish journal of parasitology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.207
H-Index - 18
eISSN - 2146-3077
pISSN - 1300-6320
DOI - 10.5152/tpd.2018.5554
Subject(s) - leishmania tropica , in vivo , in vitro , leishmania , medicine , leishmaniasis , pharmacology , cutaneous leishmaniasis , chemistry , immunology , biology , computer science , biochemistry , microbiology and biotechnology , parasite hosting , world wide web
Two pentavalent antimonials, meglumine antimoniate (Glucantime®, France) and sodium stibogluconate (Pentostam®, England), are used to treat cutaneous leishmaniasis (CL) in Turkey. The present study, serving as a guidebook for young researchers, aims to provide basis for conducting drug resistance tests and active ingredient scanning in in vitro and in vivo models.
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