Evaluation of Visceral Leishmaniasis Diagnosis Using Indirect Fluorescent Antibody Tests in 4 Pediatric Patients | Zendy

Yasemin Işık Balcı | Zendy; Meral Türk | Zendy; Arzu Ozgur | Zendy; Kazım Küçüktaşçi | Zendy

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Evaluation of Visceral Leishmaniasis Diagnosis Using Indirect Fluorescent Antibody Tests in 4 Pediatric Patients

Author(s) -

Yasemin Işık Balcı,

Meral Türk,

Arzu Ozgur,

Kazım Küçüktaşçi

Publication year - 2011

Publication title -

turkish journal of parasitology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.207

H-Index - 18

eISSN - 2146-3077

pISSN - 1300-6320

DOI - 10.5152/tpd.2011.28

Subject(s) - visceral leishmaniasis , leishmania infantum , medicine , pancytopenia , direct fluorescent antibody , hepatosplenomegaly , leishmaniasis , leishmania , antibody , serology , immunology , bone marrow , dermatology , pathology , parasite hosting , disease , world wide web , computer science

Visceral Leishmaniasis (VL) in infancy is mostly seen between the ages of 2-4,and visceral infection causes long standing fever, weakness, weight loss, hepatosplenomegaly and pancytopenia. Leishmania infantum is responsible for VL in Turkey. In this study, 4 pediatric cases of VL were analysed retrospectively. Bone marrow aspirate was obtained in two cases and Leishmania amastigotes were not obtained in these cases. Leishmania antibodies by the indirect immun fluorescent antibody test (IFAT) were positive in all cases. We consider that IFAT was a suitable alternative to parasite detection in the conclusive diagnosis of visceral leishmaniasis in pediatric patients when strong clinical suspicion is present.

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