Association of ICAM-1, VCAM-1, CYCLIN D1 and Cathepsin D with Clinicopathological Parameters in Breast Carcinoma; an Immunohistochemical Study | Zendy

Özgür Külahçı | Zendy; Hacı Hasan Esen | Zendy; Elife Aşut | Zendy; Salim Güngör | Zendy

Open Access

Association of ICAM-1, VCAM-1, CYCLIN D1 and Cathepsin D with Clinicopathological Parameters in Breast Carcinoma; an Immunohistochemical Study

Author(s) -

Özgür Külahçı,

Hacı Hasan Esen,

Elife Aşut,

Salim Güngör

Publication year - 2017

Publication title -

journal of breast health

Language(s) - English

Resource type - Journals

ISSN - 2149-1976

DOI - 10.5152/tjbh.2016.3142

Subject(s) - medicine , pathology , cyclin d1 , metastasis , breast carcinoma , progesterone receptor , breast cancer , axillary lymph nodes , immunohistochemistry , lymph node , ductal carcinoma , estrogen receptor , cancer , cell cycle

Breast carcinoma is the most common malignant tumor detected in women. The hypothesis that increased levels of adhesion molecules and Cathepsin D affect cancerous cells moving away the primary tumor and contributes to migration of the cancerous cell and may cause remote organ metastases is defended. The aim of the present study was to search the association of intracellular adhesion molecule-1 (ICAM-1), vascular adhesion molecule-1 (VCAM-1), Cyclin D1, cathepsin D immunohistochemically with clinicopathological parameters in the patients diagnosed with invasive ductal breast carcinoma.

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