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PGD management scheme for older females with balanced translocations: Do older females have less chance of balanced embryo transfer?
Author(s) -
Pınar Tulay,
Meral Gültomruk,
Necati Fındıklı,
Mustafa Bahçeci
Publication year - 2016
Publication title -
journal of the turkish-german gynecological association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.346
H-Index - 16
eISSN - 1309-0399
pISSN - 1309-0380
DOI - 10.5152/jtgga.2016.16043
Subject(s) - chromosomal translocation , robertsonian translocation , preimplantation genetic diagnosis , embryo , advanced maternal age , infertility , biology , andrology , embryo transfer , gynecology , obstetrics , genetics , medicine , pregnancy , fetus , karyotype , gene , chromosome
Carriers of reciprocal and Robertsonian translocations have a higher risk of experiencing infertility and repeated miscarriages. It is well established that with advancing maternal age, the risk of aneuploidies in embryos increases. In this study, the chance of developing balanced embryos in translocation carriers with advanced maternal age was analyzed to establish a management scheme for couples seeking fertility treatment and preimplantation genetic diagnosis (PGD).

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