Effect of polymyxin B on gram-negative bacterial infection during pregnancy | Zendy

Mukesh K. Jaiswal | Zendy; Varkha Agrawal | Zendy; Yogesh Jaiswal | Zendy

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Effect of polymyxin B on gram-negative bacterial infection during pregnancy

Author(s) -

Mukesh K. Jaiswal,

Varkha Agrawal,

Yogesh Jaiswal

Publication year - 2011

Publication title -

journal of the turkish-german gynecological association

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.346

H-Index - 16

eISSN - 1309-0399

pISSN - 1309-0380

DOI - 10.5152/jtgga.2011.17

Subject(s) - pregnancy , polymyxin b , lipopolysaccharide , polymyxin , antibiotics , fetus , embryo , gram , gestation , andrology , medicine , physiology , microbiology and biotechnology , bacteria , biology , genetics

Polymyxin B (PB) is a naturally occurring cationic cyclic decapeptide which is highly bactericidal to Gram-negative bacteria. The objective of this study was to investigate the effect of PB on the viability of developing embryos during pregnancy and to validate its protective effect on the embryotoxic effect of Gram-negative bacterial lipopolysaccharide (LPS).

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