Effect of kirenol on the interaction between the WNT/β-Catenin and RUNX2/TCF/LEF1 pathways in fracture healing in vivo | Zendy

İbrahim Karaman | Zendy; Ali Eray Günay | Zendy; Mükerrem Betül Yerer | Zendy; Eren Demirpolat | Zendy; Serap Doğan | Zendy; Arzu Yay | Zendy; İbrahim Halil Kafadar | Zendy

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Effect of kirenol on the interaction between the WNT/β-Catenin and RUNX2/TCF/LEF1 pathways in fracture healing in vivo

Author(s) -

İbrahim Karaman,

Ali Eray Günay,

Mükerrem Betül Yerer,

Eren Demirpolat,

Serap Doğan,

Arzu Yay,

İbrahim Halil Kafadar

Publication year - 2020

Publication title -

acta orthopaedica et traumatologica turcica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.586

H-Index - 28

eISSN - 2589-1294

pISSN - 1017-995X

DOI - 10.5152/j.aott.2020.03.529

Subject(s) - medicine , bone healing , wnt signaling pathway , in vivo , intramedullary rod , callus , femur , tibia , surgery , signal transduction , biochemistry , chemistry , genetics , microbiology and biotechnology , biology

This study aimed to determine the effects of a natural diterpenoid, kirenol, on fracture healing in vivo in an experimental rat model of femur fracture and investigate its potential mechanism of action via the Wnt/β-catenin pathway.

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