Diagnostic Accuracy of Tru-Cut Biopsy for Soft Tissue Tumors

Biopsy is a crucial initial diagnostic step for the identification of soft tissue lesions of the musculoskeletal system (1). Benign and small soft tissue lesions, such as cysts, small lipomas, inflammatory nodules, dermatofibroma, or other benign fibrous lesions, do not require surgical treatment. However, for lesions >4 cm, a histological confirmation is necessary for the diagnosis (2). A fine needle aspiration, tru-cut, or open biopsy may have specific advantages and disadvantages with the aim of obtaining a representative tissue sample with minimal trauma leading to a correct surgical approach for a subsequent resection to facilitate limb-sparing procedures (3).