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Is Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome (CANVAS) a Vestibular Ganglionopathy?
Author(s) -
Darío Andrés Yacovino,
Estefanía Zanotti,
Timothy C. Hain
Publication year - 2019
Publication title -
the journal of international advanced otology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.518
H-Index - 13
eISSN - 2148-3817
pISSN - 1308-7649
DOI - 10.5152/iao.2019.7068
Subject(s) - medicine , vestibular system , vestibular nerve , scarpa's ganglion , vestibular evoked myogenic potential , audiology , semicircular canal , saccule , anatomy , posterior semicircular canal , vestibule , cerebellar ataxia , ataxia , psychiatry
CANVAS is an acronym for cerebellar ataxia, neuropathy and vestibular areflexia syndrome. Limited autopsy data has suggested that CANVAS is caused by a focal dorsal root ganglionopathy that damages Scarpa's (vestibular) ganglion, but spares the Spiral (hearing) ganglion. If the vestibular areflexia of CANVAS is in fact due to ganglionopathy, then there should be global reduction of all vestibular responses.

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