Electrophysiological and Histopathological Evaluation of Effects of Sodium-2 Mercaptoethanesulfonate Used for Middle Ear Surgery on Facial Nerve Functions | Zendy

Oğuz Kadir Eğilmez | Zendy; Numan Kökten | Zendy; Mustafa Baran | Zendy; M. Tayyar Kalcıoğlu | Zendy; Işın Doğan Ekici | Zendy; Muhammet Tekın | Zendy

Open Access

Electrophysiological and Histopathological Evaluation of Effects of Sodium-2 Mercaptoethanesulfonate Used for Middle Ear Surgery on Facial Nerve Functions

Author(s) -

Oğuz Kadir Eğilmez,

Numan Kökten,

Mustafa Baran,

M. Tayyar Kalcıoğlu,

Işın Doğan Ekici,

Muhammet Tekın

Publication year - 2017

Publication title -

the journal of international advanced otology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.518

H-Index - 13

eISSN - 2148-3817

pISSN - 1308-7649

DOI - 10.5152/iao.2017.3888

Subject(s) - mesna , medicine , facial nerve , electromyography , anesthesia , histopathology , surgery , anatomy , pathology , chemotherapy , ifosfamide , psychiatry , etoposide

Sodium-2-mercaptoethanesulfonate (MESNA) is widely used in medicine because of its antioxidant and mucolytic effects. In recent years, it has been used in otologic surgery. Because it cleaves disulfide bonds, it is used to easily dissect the epithelial matrix in cholesteatoma and atelectasis. In this study, we hypothesized that MESNA does not have any toxic effect on the facial nerve, and the effects of MESNA on the facial nerve were examined histologically and electrophysiologically.

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