The Effects of MESNA on the Facial Nerve, an Experimental Animal Study | Zendy

Deniz Baklacı | Zendy; Rauf Oğuzhan Kum | Zendy; Sezer Kulaçoğlu | Zendy; Yavuz Fuat Yılmaz | Zendy; Müge Özcan | Zendy

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The Effects of MESNA on the Facial Nerve, an Experimental Animal Study

Author(s) -

Deniz Baklacı,

Rauf Oğuzhan Kum,

Sezer Kulaçoğlu,

Yavuz Fuat Yılmaz,

Müge Özcan

Publication year - 2017

Publication title -

the journal of international advanced otology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.518

H-Index - 13

eISSN - 2148-3817

pISSN - 1308-7649

DOI - 10.5152/iao.2017.3593

Subject(s) - mesna , medicine , facial nerve , saline , anesthesia , reflex , cheek , corneal reflex , anatomy , surgery , ifosfamide , chemotherapy , etoposide

MESNA (Sodium-2-mercaptoethanesulfonate) is a mucolytic substance that is used for chemically assisted tissue dissection in various surgical operations. The aim of this study was to address the issue of possible neurotoxicity from topical administration of MESNA solution on the facial nerve. We used different concentrations of MESNA solution and evaluated their effects on facial nerve by histopathological and functional analysis.

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