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Comparative Study between the use of Melatonin and A Solution with Melatonin, Tryptophan, and Vitamin B6 as an Inducer of Spontaneous Sleep in Children During an Auditory Response Test: An Alternative to Commonly Used Sedative Drugs
Author(s) -
Antonio Della Volpe,
Antonietta De Lucia,
Clementina Pirozzi,
Vincenzo Pastore
Publication year - 2017
Publication title -
the journal of international advanced otology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.518
H-Index - 13
eISSN - 2148-3817
pISSN - 1308-7649
DOI - 10.5152/iao.2017.3054
Subject(s) - melatonin , medicine , sedative , tryptophan , regimen , endocrinology , pharmacology , biochemistry , chemistry , amino acid
An elective investigation into the early diagnosis of deafness in children under the age of 4-5 years is performed using auditory evoked potentials of auditory brainstem responses (ABRs). In case of pediatric patients, the major difficulty includes being examined during spontaneous sleep, which is complicated to obtain, especially in the age range of 12 to 72 months. Recently, melatonin has been used as a "sleep inducer" in diagnostic tests with positive results. Our aim was to evaluate the use of melatonin and of a solution containing melatonin, tryptophan, and vitamin B6 as an inducer of spontaneous sleep on repeated ABR analyses as well as to evaluate the reduction in analyses with sedative drugs in case of uncooperative patients.

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