New Inflammation Parameters in Sudden Sensorineural Hearing Loss: Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio
Author(s) -
Aykut İkincioğulları,
Sabri Köseoğlu,
Murat Kılıç,
Doğan Atan,
Kürşat Murat Özcan,
Mehmet Ali Çetin,
Serdar Ensarı,
Hacı Hüseyin Dere
Publication year - 2015
Publication title -
the journal of international advanced otology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.518
H-Index - 13
eISSN - 2148-3817
pISSN - 1308-7649
DOI - 10.5152/iao.2014.76
Subject(s) - medicine , lymphocyte , inflammation , neutrophil to lymphocyte ratio , immunology , platelet , sensorineural hearing loss , hearing loss , audiology
rd, 10 th , and 30 th days of the hearing loss. All patients received 1 mg/kg IV prednisolone treatment in tapered amounts to be completed in 15 days. Based on the improvements seen in the audiograms, the patients were divided into two groups: responders and non-responders to treatment. RESULTS: PLR and NLR values of the patient group were significantly higher than in the control group (p<0.001, p<0.001). Furthermore, patients who responded to treatment had significantly higher NLR values than those who did not respond (p=0.010). CONCLUSION: In this study, NLR and PLR values were found to be significantly high in SSNHL patients. PLR value was investigated for the first time in the literature in SSNHL patients. NLR and PLR values are parameters that aid in the diagnosis of SSNHL. Moreover, SSNHL patients who had higher NLR values responded to the treatment better.
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