Pulmonary Sclerosing Hemangioma Exhibiting a High KI-67 Proliferation Index
Author(s) -
Elif Ülker Akyıldız,
Ahmet Sami Bayram,
Akgül Arıcı,
Mehtap Kasap
Publication year - 2012
Publication title -
erciyes medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.101
H-Index - 11
ISSN - 1300-199X
DOI - 10.5152/etd.2012.28
Subject(s) - index (typography) , hemangioma , proliferation index , medicine , pathology , computer science , immunohistochemistry , world wide web
OZET Pulmonary sclerosing hemangioma (PSH) is a rare pulmonary neoplasm. This tumour was originally thought to be a variant lesion of hemangioma. Today, however, it has been elucidated to be a tumour of epithelial origin derived from the primitive respiratory epithelium. Previous studies have reported a low Ki67 proliferation index in cases of pulmonary sclerosing hemangioma (1.4-2.2%). Moreover, the biological nature of this neoplasm, which rarely tends to metastasise to the lymph nodes, has yet to be thoroughly elucidated. A female patient in whom PSH exhibiting a high Ki-67 proliferation index was detected in the lung during follow-up for lymphoma is reported in the present study. While the Ki 67 proliferation index was 3-4% in some areas, it increased up to 15-20% in other areas. No recurrence or metastases were evident at postoperative follow-up.
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