Loss of Nuclear ARID-1A Expressions Is Associated with Hormone Receptor Status in Breast Cancers | Zendy

Melek Ünçel | Zendy; Gülden Diniz | Zendy; Gamze Aköz | Zendy; Zübeyde Yıldırım Ekin | Zendy; Sevil Saydan | Zendy; Serdar Yardim | Zendy; Semra Salimoğlu | Zendy

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Loss of Nuclear ARID-1A Expressions Is Associated with Hormone Receptor Status in Breast Cancers

Author(s) -

Melek Ünçel,

Gülden Diniz,

Gamze Aköz,

Zübeyde Yıldırım Ekin,

Sevil Saydan,

Serdar Yardim,

Semra Salimoğlu

Publication year - 2019

Publication title -

meme sağlığı dergisi/meme sağlığı dergisi

Language(s) - English

Resource type - Journals

eISSN - 1306-0953

pISSN - 1306-0945

DOI - 10.5152/ejbh.2019.4677

Subject(s) - arid1a , breast cancer , progesterone receptor , breast carcinoma , pathological , oncology , estrogen receptor , medicine , cancer , cancer research , hormone receptor , lymph node , biology , hormone , receptor , estrogen , gene , biochemistry , mutation

Breast cancer is the most common cancer among women worldwide. Adenine thymine-rich interactive domain 1A (ARIDIA) is a tumor suppressor gene involved in chromatin remodeling and it encodes the ARIDIA protein. Recent studies have shown the loss of ARIDIA protein expression in different carcinomas may have a prognostic significance. In the present study, we aimed to evaluate the interactions between ARIDIA loss and molecular subtypes of breast carcinomas.

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