HER-2/Neu and Hormone Receptor Analysis in Breast Carcinomas and Their Association with Clinicopathologic Parameters | Zendy

Reşit Doğan Köseoğlu | Zendy; Fatma Markoç | Zendy; Ahmet Müslehiddinoğlu | Zendy; Ayse Burcu Ileri | Zendy; Faik Alev Deresoy | Zendy; Ílker Etikán | Zendy

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HER-2/Neu and Hormone Receptor Analysis in Breast Carcinomas and Their Association with Clinicopathologic Parameters

Author(s) -

Reşit Doğan Köseoğlu,

Fatma Markoç,

Ahmet Müslehiddinoğlu,

Ayse Burcu Ileri,

Faik Alev Deresoy,

Ílker Etikán

Publication year - 2018

Publication title -

meme sağlığı dergisi/meme sağlığı dergisi

Language(s) - English

Resource type - Journals

eISSN - 1306-0953

pISSN - 1306-0945

DOI - 10.5152/ejbh.2018.4118

Subject(s) - immunohistochemistry , concordance , progesterone receptor , breast cancer , medicine , her2/neu , estrogen receptor , fluorescence in situ hybridization , oncology , axilla , hormone receptor , lymph node , pathology , biology , cancer , gene , biochemistry , chromosome

Invasive breast carcinomas of no special type (IC-NST) are the heterogeneous tumours showing distinct prognostic features even in patients with similar clinicopathological characteristics. To date, many clinicopathological data have been analyzed to make a guess about prognosis and to determine treatment modality. In this study, HER-2/neu status was analyzed by using both immunohistochemical (IHC) and fluorescence in situ hybridization (FISH) methods, and its correlations with hormone receptor status and clinicopathological parameters were investigated.

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